Toward Closing the Loop in Image-to-Image Conversion in Radiotherapy: A Quality Control Tool to Predict Synthetic Computed Tomography Hounsfield Unit Accuracy
Published by
Journal of Imaging
Summary
journal-article
About
I am - a curious scientist, dedicated to translate state-of-the-art research into practice - a passionate instructor, enjoying to guide, educate and empower emerging scientist - an accountable and efficient project manager, committed to motivate stakeholders for a joined vision - an eager networker, who loves to connect people facilitating scientific synergies
Work
University Bern
|Prof for applied data sciences and decision support systems
Switzerland
→
sitem-insel AG
|adademic lead / director
Switzerland
→
TU Dresden
|Affiliated Professor
Germany
→
Hochschule für Life Sciences FHNW
|Professor
Switzerland
→
Paul Scherrer Institute
|Guest Scientist
Switzerland
→
University Hospital Cologne
|Scientific Project Manager
Germany
→
Carl von Ossietzky Universität Oldenburg
|Guest Professor
Germany
→
University Medical Center Groningen
|Associate Professor / IUS Promovendi
Netherlands
→
Institute of Cancer Research
|PostDoc
United Kingdom of Great Britain and Northern Ireland
→
University Medical Center Utrecht
|Visiting Research Fellow
Netherlands
→
Paul Scherrer Institute
|PostDoc / Research Assistant
Switzerland
→
ETH Zurich
|Research Assistant
Switzerland
→
National Institute of Radiological Sciences
|Visiting Research Fellow
Japan
→
Education
Cologne Business School
Germany
→
EMBA
Heidelberg University
Germany
→
PhD in Physics
Heidelberg University
Germany
→
Diploma (M.Sc.) in Physics
Heidelberg University
Germany
→
M.Sc. Medical Physics
Publications
Possible association of dose rate and the development of late visual toxicity for patients with intracranial tumours treated with pencil beam scanned proton therapy
Published by
Radiation Oncology
Summary
journal-article
Toward Closing the Loop in Image-to-Image Conversion in Radiotherapy: A Quality Control Tool to Predict Synthetic Computed Tomography Hounsfield Unit Accuracy
Published by
Journal of Imaging
Summary
journal-article
Imaging in Particle Therapy
Summary
edited-book
Technical note: development of a simulation framework, enabling the investigation of locally tuned single energy proton radiography
Published by
Biomedical Physics & Engineering Express
Summary
journal-article
A review of the clinical introduction of 4D particle therapy research concepts
Published by
Physics and Imaging in Radiation Oncology
Summary
journal-article
Technical note: Flat panel proton radiography with a patient specific imaging field for accurate WEPL assessment
Published by
Medical Physics
Summary
journal-article
A survey of practice patterns for adaptive particle therapy for interfractional changes
Published by
Physics and Imaging in Radiation Oncology
Summary
journal-article
A survey of practice patterns for real-time intrafractional motion-management in particle therapy
Published by
Physics and Imaging in Radiation Oncology
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journal-article
Robustness assessment of clinical adaptive proton and photon radiotherapy for oesophageal cancer in the model-based approach
Published by
Radiotherapy and Oncology
Summary
journal-article
Deep learning based 4D‐synthetic CTs from sparse‐view CBCTs for dose calculations in adaptive proton therapy
Published by
Medical Physics
Summary
journal-article
Clinical necessity of multi-image based (4DMIB) optimization for targets affected by respiratory motion and treated with scanned particle therapy – A comprehensive review
Published by
Radiotherapy and Oncology
Summary
journal-article
Management of Motion and Anatomical Variations in Charged Particle Therapy: Past, Present, and Into the Future
Published by
Frontiers in Oncology
Summary
journal-article
Management of Motion and Anatomical Variations in Charged Particle Therapy: Past, Present, and Into the Future
Published by
Frontiers in Oncology
Summary
journal-article
Anthropomorphic lung phantom based validation of in-room proton therapy 4D-CBCT image correction for dose calculation
Published by
Zeitschrift für Medizinische Physik
Summary
journal-article
Diaphragm-Based Position Verification to Improve Daily Target Dose Coverage in Proton and Photon Radiation Therapy Treatment of Distal Esophageal Cancer
Published by
International Journal of Radiation Oncology*Biology*Physics
Summary
journal-article
Clinical practice vs. state-of-the-art research and future visions: Report on the 4D treatment planning workshop for particle therapy – Edition 2018 and 2019
Published by
Physica Medica
Summary
journal-article
Clinical suitability of deep learning based synthetic CTs for adaptive proton therapy of lung cancer
Published by
Medical Physics
Summary
journal-article
Optimizing calibration settings for accurate water equivalent path length assessment using flat panel proton radiography
Published by
Physics in Medicine & Biology
Summary
journal-article
Executive Summary of Clinical and Technical Guidelines for Esophageal Cancer Proton Beam Therapy From the Particle Therapy Co-Operative Group Thoracic and Gastrointestinal Subcommittees
Published by
Frontiers in Oncology
Summary
journal-article
Executive Summary of Clinical and Technical Guidelines for Esophageal Cancer Proton Beam Therapy From the Particle Therapy Co-Operative Group Thoracic and Gastrointestinal Subcommittees
Published by
Frontiers in Oncology
Summary
journal-article
Assessment of a diaphragm override strategy for robustly optimized proton therapy planning for esophageal cancer patients
Published by
Medical Physics
Summary
journal-article
Range probing as a quality control tool for CBCT‐based synthetic CTs: In vivo application for head and neck cancer patients
Published by
Medical Physics
Summary
journal-article
Dosimetric influence of deformable image registration uncertainties on propagated structures for online daily adaptive proton therapy of lung cancer patients
Published by
Radiotherapy and Oncology
Summary
journal-article
An approach for estimating dosimetric uncertainties in deformable dose accumulation in pencil beam scanning proton therapy for lung cancer
Published by
Physics in Medicine & Biology
Summary
journal-article
A comprehensive motion analysis – consequences for high precision image-guided radiotherapy of esophageal cancer patients
Published by
Acta Oncologica
Summary
journal-article
Towards the clinical implementation of intensity-modulated proton therapy for thoracic indications with moderate motion: Robust optimised plan evaluation by means of patient and machine specific information
Published by
Radiotherapy and Oncology
Summary
journal-article
Roadmap: proton therapy physics and biology
Published by
Physics in Medicine & Biology
Summary
journal-article
Consensus Statement on Proton Therapy in Mesothelioma
Published by
Practical Radiation Oncology
Summary
journal-article
Deep learning prediction of proton and photon dose distributions for paediatric abdominal tumours
Published by
Radiotherapy and Oncology
Summary
journal-article
Technical Note: First report on an in vivo range probing quality control procedure for scanned proton beam therapy in head and neck cancer patients
Published by
Medical Physics
Summary
journal-article
Head and neck IMPT probabilistic dose accumulation: Feasibility of a 2 mm setup uncertainty setting
Published by
Radiotherapy and Oncology
Summary
journal-article
Evaluation of continuous beam rescanning versus pulsed beam in pencil beam scanned proton therapy for lung tumours
Published by
Physics in Medicine & Biology
Summary
journal-article
Classification of various sources of error in range assessment using proton radiography and neural networks in head and neck cancer patients
Published by
Physics in Medicine & Biology
Summary
journal-article
Comparison of the suitability of CBCT- and MR-based synthetic CTs for daily adaptive proton therapy in head and neck patients
Published by
Physics in Medicine & Biology
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journal-article
Deep learning-enabled MRI-only photon and proton therapy treatment planning for paediatric abdominal tumours
Published by
Radiotherapy and Oncology
Summary
journal-article
MR-guided proton therapy: a review and a preview
Published by
Radiation Oncology
Summary
journal-article
Technical Note: 4D cone‐beam CT reconstruction from sparse‐view CBCT data for daily motion assessment in pencil beam scanned proton therapy (PBS‐PT)
Published by
Medical Physics
Summary
journal-article
Weekly robustness evaluation of intensity-modulated proton therapy for oesophageal cancer
Published by
Radiotherapy and Oncology
Summary
journal-article
Evaluation of interplay and organ motion effects by means of 4D dose reconstruction and accumulation
Published by
Radiotherapy and Oncology
Summary
journal-article
Feasibility of patient specific quality assurance for proton therapy based on independent dose calculation and predicted outcomes
Published by
Radiotherapy and Oncology
Summary
journal-article
Investigation of inter‐fraction target motion variations in the context of pencil beam scanned proton therapy in non‐small cell lung cancer patients
Published by
Medical Physics
Summary
journal-article
Assessment of range uncertainty in lung-like tissue using a porcine lung phantom and proton radiography
Published by
Physics in Medicine & Biology
Summary
journal-article
Time-resolved dosimetry for validation of 4D dose calculation in PBS proton therapy
Published by
Physics in Medicine & Biology
Summary
journal-article
Deformable image registration uncertainty for inter-fractional dose accumulation of lung cancer proton therapy
Published by
Radiotherapy and Oncology
Summary
journal-article
Comparison of CBCT based synthetic CT methods suitable for proton dose calculations in adaptive proton therapy
Published by
Physics in Medicine & Biology
Summary
journal-article
Platform for automatic patient quality assurance via Monte Carlo simulations in proton therapy
Published by
Physica Medica
Summary
journal-article
Organ sparing potential and inter-fraction robustness of adaptive intensity modulated proton therapy for lung cancer
Published by
Acta Oncologica
Summary
journal-article
Evaluating the benefit of PBS vs. VMAT dose distributions in terms of dosimetric sparing and robustness against inter-fraction anatomical changes for pediatric abdominal tumors
Published by
Radiotherapy and Oncology
Summary
journal-article
Real-time intrafraction motion monitoring in external beam radiotherapy
Published by
Physics in Medicine & Biology
Summary
journal-article
In vitro biological response of cancer and normal tissue cells to proton irradiation not affected by an added magnetic field
Published by
Radiotherapy and Oncology
Summary
journal-article
Comprehensive 4D robustness evaluation for pencil beam scanned proton plans
Published by
Radiotherapy and Oncology
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journal-article
Log file-based dose reconstruction and accumulation for 4D adaptive pencil beam scanned proton therapy in a clinical treatment planning system: Implementation and proof-of-concept
Published by
Medical Physics
Summary
journal-article
Feasibility of MRI-only photon and proton dose calculations for pediatric patients with abdominal tumors
Published by
Physics in Medicine & Biology
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journal-article
MR-only guided proton therapy : advances, future perspectives and challenges
Published by
MRI in Radiation Therapy
Summary
journal-article
Feasibility of proton pencil beam scanning treatment of free-breathing lung cancer patients
Published by
Acta Oncologica
Summary
journal-article
Reproducibility of the lung anatomy under active breathing coordinator control: Dosimetric consequences for scanned proton treatments
Published by
Medical Physics
Summary
journal-article
Motion management in particle therapy
Published by
Medical Physics
Summary
journal-article
Clinical implementations of 4D pencil beam scanned particle therapy: Report on the 4D treatment planning workshop 2016 and 2017
Published by
Physica Medica
Summary
journal-article
Assessment of dosimetric errors induced by deformable image registration methods in 4D pencil beam scanned proton treatment planning for liver tumours
Published by
Radiotherapy and Oncology
Summary
journal-article
An automated, quantitative, and case-specific evaluation of deformable image registration in computed tomography images
Published by
Physics in Medicine & Biology
Summary
journal-article
Adaptive radiotherapy
Published by
edizinische Physik: Grundlagen – Bildgebung – Therapie – Technik
Summary
book-chapter
Precision and Uncertainties for Moving Targets
Published by
Proton Therapy Physics
Summary
book-chapter
Consensus Guidelines for Implementing Pencil-Beam Scanning Proton Therapy for Thoracic Malignancies on Behalf of the PTCOG Thoracic and Lymphoma Subcommittee
Published by
International Journal of Radiation Oncology*Biology*Physics
Summary
journal-article
Iterative framework for the joint segmentation and CT synthesis of MR images: application to MRI-only radiotherapy treatment planning
Published by
Physics in Medicine and Biology
Summary
journal-article
An anthropomorphic breathing phantom of the thorax for testing new motion mitigation techniques for pencil beam scanning proton therapy
Published by
Physics in Medicine and Biology
Summary
journal-article
Evaluation of a multi-atlas CT synthesis approach for MRI-only radiotherapy treatment planning
Published by
Physica Medica
Summary
journal-article
Required transition from research to clinical application: Report on the 4D treatment planning workshops 2014 and 2015
Published by
Physica Medica
Summary
journal-article
Robustness of the Voluntary Breath-Hold Approach for the Treatment of Peripheral Lung Tumors Using Hypofractionated Pencil Beam Scanning Proton Therapy
Published by
International Journal of Radiation Oncology*Biology*Physics
Summary
journal-article
Deep Inspiration Breath Hold—Based Radiation Therapy: A Clinical Review
Published by
International Journal of Radiation Oncology*Biology*Physics
Summary
journal-article
Improving 4D plan quality for PBS-based liver tumour treatments by combining online image guided beam gating with rescanning
Published by
Physics in Medicine and Biology
Summary
journal-article
Motion Managment
Published by
Principles and Practice of Proton Beam Therapy
Summary
book-chapter
Online image guided tumour tracking with scanned proton beams: a comprehensive simulation study
Published by
Physics in Medicine and Biology
Summary
journal-article
Advances in 4D Treatment Planning for Scanned Particle Beam Therapy — Report of Dedicated Workshops
Published by
Technology in Cancer Research & Treatment
Summary
journal-article
Challenges of radiotherapy: Report on the 4D treatment planning workshop 2013
Published by
Physica Medica
Summary
journal-article
In the context of radiosurgery – Pros and cons of rescanning as a solution for treating moving targets with scanned particle beams
Published by
Physica Medica
Summary
journal-article
Quantifying the impact of respiratory-gated 4D CT acquisition on thoracic image quality: A digital phantom study
Published by
Medical Physics
Summary
journal-article
Current status and future prospects of multi-dimensional image-guided particle therapy
Published by
Radiological Physics and Technology
Summary
journal-article
Deformable motion reconstruction for scanned proton beam therapy using on-line x-ray imaging
Published by
Physics in Medicine and Biology
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journal-article
Comparative study of layered and volumetric rescanning for different scanning speeds of proton beam in liver patients
Published by
Physics in Medicine and Biology
Summary
journal-article
Adequate margin definition for scanned particle therapy in the incidence of intrafractional motion
Published by
Physics in Medicine and Biology
Summary
journal-article
In vivo proton range verification: a review
Published by
Physics in Medicine and Biology
Summary
journal-article
Mapping motion from 4D-MRI to 3D-CT for use in 4D dose calculations: A technical feasibility study
Published by
Medical Physics
Summary
journal-article
Respiratory liver motion estimation and its effect on scanned proton beam therapy
Published by
Physics in Medicine and Biology
Summary
journal-article
Scanned proton radiotherapy for mobile targets—the effectiveness of re-scanning in the context of different treatment planning approaches and for different motion characteristics
Published by
Physics in Medicine and Biology
Summary
journal-article
Extension and validation of an analytical model for<i>in vivo</i>PET verification of proton therapy—a phantom and clinical study
Published by
Physics in Medicine and Biology
Summary
journal-article
Accuracy of Proton Beam Range Verification Using Post-Treatment Positron Emission Tomography/Computed Tomography as Function of Treatment Site
Published by
International Journal of Radiation Oncology*Biology*Physics
Summary
journal-article
Special report: Workshop on 4D-treatment planning in actively scanned particle therapy-Recommendations, technical challenges, and future research directions
Published by
Medical Physics
Summary
journal-article
Systematic analysis of biological and physical limitations of proton beam range verification with offline PET/CT scans
Published by
Physics in Medicine and Biology
Summary
journal-article
Quantitative assessment of the physical potential of proton beam range verification with PET/CT
Published by
Physics in Medicine and Biology
Summary
journal-article
PET imaging for treatment verification of ion therapy: Implementation and experience at GSI Darmstadt and MGH Boston
Published by
Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment
Summary
journal-article
Patient Study of In Vivo Verification of Beam Delivery and Range, Using Positron Emission Tomography and Computed Tomography Imaging After Proton Therapy
Published by
International Journal of Radiation Oncology*Biology*Physics
Summary
journal-article
Optimization of extracranial stereotactic radiation therapy of small lung lesions using accurate dose calculation algorithms
Published by
Radiation Oncology
Summary
journal-article